SalmoNet 2.0

An integrated multi-layered network of Salmonella

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Features

  • An integrated network resource containing regulatory, metabolic and protein-protein interactions
  • For 20 Salmonella strains classified as gastro-intestinal or extra-intestinal pathogens
  • An interaction resource with manually curated, high-throughput and predicted interactions
  • Provides a strain specific and consensus networks
  • Can be downloaded in a user-specified content and format

Statistics

Components

Strains
20
Orthologous Genes
3 854
Orthologous Transcription factors
127
Orthologous Metabolic enzymes
1 220

Interactions

Total interactions
270 196
Protein-protein interactions
143 684
Regulatory interactions
64 236
Metabolic interactions
62 276

Strains

  • Salmonella agona (strain SL483)
  • Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)
  • Salmonella bongori (strain ATCC 43975 / DSM 13772 / NCTC 12419)
  • Salmonella choleraesuis (strain SC-B67)
  • Salmonella dublin (strain CT_02021853)
  • Salmonella enteritidis PT4 (strain P125109)
  • Salmonella gallinarum (strain 287/91 / NCTC 13346)
  • Salmonella heidelberg (strain SL476)
  • Salmonella newport (strain SL254)
  • Salmonella paratyphi A (strain AKU_12601)
  • Salmonella paratyphi A (strain ATCC 9150 / SARB42)
  • Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)
  • Salmonella paratyphi C (strain RKS4594)
  • Salmonella schwarzengrund (strain CVM19633)
  • Salmonella typhi
  • Salmonella typhimurium (strain 14028s / SGSC 2262)
  • Salmonella typhimurium (strain 4/74)
  • Salmonella typhimurium (strain D23580)
  • Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
  • Salmonella typhimurium (strain SL1344)

Cite

SalmoNet, an integrated network of ten Salmonella enterica strains reveals common and distinct pathways to host adaptation

Métris A., Sudhakar P., Fazekas D., Demeter A., Ari E., Branchu P, Kingsley R.A., Baranyi J., Korcsmáros T.

npj Systems Biology and Applications 3, Article number: 31 (2017) doi:10.1038/s41540-017-0034-z

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